# they have gone away looking for many difficulties
Possible meanings are 1) "they have made many sinful plans" or 2) "they have made their own lives difficult."
# they have gone away
Here the word "they" refers to "humanity." This speaks of humanity changing from being upright to not being upright as if they were going from one place to another. (See: [[rc://en/ta/man/jit/figs-metaphor]])