# such as has not been from the beginning
"greater than there has ever been since the beginning of the world." This describes how great and terrible the tribulation will be. There has never been a tribulation as terrible as this one will be.
# the beginning of creation, which God created
the beginning of creation, when God created the world
# no, nor ever will be again
"and greater than there will ever be again" or "and after that tribulation, there will never again be a tribulation like it"